Searchable abstracts of presentations at key conferences in endocrinology

ea0035s9.1 | EYES Session - Cold metabolic inflammation in obesity: ignored complication and treatment target? | ECE2014

Introducing EYES: European Young Endocrine Scientists

Schulte Dominik M

The ‘European Young Endocrine Scientists’ (EYES) founded in 2011, is a committee under the patronage of the European Society of Endocinology (ESE). The primary goal of this committee is to increase the mutual exchange of ideas and knowledge between young endocrinologists – from basic researchers to clinicians – across Europe in the initial stages of their career. EYES enables young endocrinologists (<35 years) from all ESE member societies to actively c...

ea0041gp138 | Obesity | ECE2016

Dietary and weight loss effects on human gut microbiome diversity and metabolism

Fangmann Daniela , Heinsen Femke-Anouska , Schulte Dominik M , Ruhlemann Malte-Christoph , Turk Kathrin , Settgast Ute , Muller Nike , Lieb Wolfgang , Baines John F , Schreiber Stefan , Franke Andre , Laudes Matthias

Introduction: Changes in the gut microbiome have been associated with the development of obesity. The aim of the present study was to examine i) the effect of a formula based very-low-calorie weight loss diet (VLCD) on the gut microbiome of obese humans and ii) whether if potential changes are sustained during weight maintenance.Patients and methods: The study consisted of 3 months VLCD (~800 kcal/d) followed by 3 months of weight maintenance. 18 obese h...

ea0041ep195 | Cardiovascular Endocrinology and Lipid Metabolism | ECE2016

Liposomal prednisolone promotes macrophage necroptosis in experimental atherosclerosis: does this explain atherogenesis in Cushing’s disease?

Schulte Dominik M , van der Valk Fleur M , Meiler Svenja , Tang Jun , Zheng Kang He , van den Bossche Jan , Seijkens Tom , Laudes Matthias , de Winther Menno , Lutgens Esther , Alaarg Amr , Metselaar Josbert M , Dallinga-Thie Geesje M , Mulder Willem J M , Stroes Erik S G , Hamers Anouk A J

Introduction: Patients with a Cushing syndrome – a glucocorticoid driven disease–have a high risk for cardiovascular events, mainly due to atherosclerosis. Atherosclerosis is a lipid-driven inflammatory disease, for which novel anti-inflammatory strategies like glucocorticoids are under evaluation. Thus, the impact of glucocorticoids on atherosclerosis seems to be ambiguous: pro- or anti-inflammatory. To avoid systemic glucocorticoid side effects contributing to athe...